572 INTRAMYOCARDIAL CALCIFICATION IN APICAL HYPERTROPHIC CARDIOMYOPATHY ASSESSED USING MULTIMODALITY IMAGING: OUR CASE SERIES
نویسندگان
چکیده
Abstract Introduction Apical Hypertrophic Cardiomyopathy (ApHCM) characterized by persistent diastolic apical contraction results in dynamic small-vessel obstruction with microvascular ischemia. Of note, endomyocardial fibrosis (EMF) and calcification are described only few patients. Case presentation We report 5 cases of ApHCM intramyocardial calcification. They presented characteristic ECG pattern at echocardiogram. All patients a preserved ejection fraction (EF), except for one patient mild reduced EF. Global longitudinal strain was 3 Diastolic dysfunction evidenced Right ventricle involvement detected only.On cardiac magnetic resonance, superficial hypo-intense component, compatible calcium deep layer featured late gadolinium enhancement (LGE) related to fibrotic tissue, were revealed. LGE present all the apex. One an aneurysm, high ESC-SCD risk score ICD implantation. Conclusion EMF pathologic hallmarks endocardium myocardium scarring, evolving dystrophic In clinical practice, minority develops calcifications. Our series is largest literature. Analyzing patients’ history, inflammatory trigger evident them, particularly severe chronic kidney disease, diabetes, degree obesity, malaria infection, peripheral microangiopathy form thalassemia. This could demonstrate pathophysiological relation between fibrosis, ischemia due hypertrophy conditions coexistence. A broader case evaluate any correlation their long-term outcome management strategies.
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2022
ISSN: ['1520-765X', '1554-2815']
DOI: https://doi.org/10.1093/eurheartjsupp/suac121.225